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Yan Zhao Selected Research

Small Interfering RNA (siRNA)

3/2023Simultaneous Knockdown of Immune Suppressive Markers by Tumor Microenvironment-Responsive Multifaceted Prodrug Nanomedicine.
1/2023ALK-JNK signaling promotes NLRP3 inflammasome activation and pyroptosis via NEK7 during Streptococcus pneumoniae infection.
9/2022Virus-like siRNA construct dynamically responsive to sequential microenvironments for potent RNA interference.
12/2021Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
10/2021Novel HIF-1-target gene isthmin1 contributes to hypoxia-induced hyperpermeability of pulmonary microvascular endothelial cells monolayers.
1/2021LINC00265/miR-4500 Axis Accelerates Acute Lymphoblastic Leukemia Progression by Enhancing STAT3 Signals.
12/2020Tumor-Targeted Anti-VEGF RNAi Capable of Sequentially Responding to Intracellular Microenvironments for Potent Systemic Tumor Suppression.
11/2020miR-34a regulates lipid metabolism by targeting SIRT1 in non-alcoholic fatty liver disease with iron overload.
11/2019Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion.
5/2019Knockdown of ISOC1 suppresses cell proliferation in pancreatic cancer in vitro.
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Yan Zhao Research Topics

Disease

449Neoplasms (Cancer)
05/2024 - 12/2002
141Inflammation (Inflammations)
04/2024 - 01/2008
118Infections
05/2024 - 12/2004
83Hepatocellular Carcinoma (Hepatoma)
02/2024 - 04/2002
82Neoplasm Metastasis (Metastasis)
04/2024 - 04/2002
74Stomach Neoplasms (Stomach Cancer)
04/2024 - 02/2002
43Carcinogenesis
02/2024 - 10/2008
43Wounds and Injuries (Trauma)
09/2023 - 01/2008
42Obesity
04/2024 - 01/2013
41Body Weight (Weight, Body)
12/2023 - 02/2009
40Breast Neoplasms (Breast Cancer)
11/2023 - 02/2002
39Carcinoma (Carcinomatosis)
02/2024 - 12/2002
37COVID-19
03/2024 - 01/2020
34Insulin Resistance
12/2023 - 03/2010
32Rheumatoid Arthritis
04/2024 - 06/2002
32Fibrosis (Cirrhosis)
10/2023 - 08/2004
31Atherosclerosis
01/2024 - 11/2007
30Hypoxia (Hypoxemia)
01/2024 - 11/2012
29Acute Lung Injury
11/2023 - 05/2008
28Ischemia
02/2024 - 08/2007
27Systemic Lupus Erythematosus (Libman-Sacks Disease)
03/2024 - 06/2002
27Pain (Aches)
12/2023 - 04/2006
26Liver Cirrhosis (Hepatic Cirrhosis)
12/2024 - 05/2005
26Hemorrhage
04/2024 - 10/2003
25Necrosis
12/2024 - 03/2005
25Liver Diseases (Liver Disease)
12/2024 - 12/2007
25Lymphoma (Lymphomas)
03/2024 - 09/2005
25Traumatic Brain Injuries (Traumatic Brain Injury)
08/2023 - 01/2009
24Stroke (Strokes)
04/2024 - 01/2012
22Prostatic Neoplasms (Prostate Cancer)
05/2024 - 01/2006
22Cognitive Dysfunction
04/2024 - 11/2013
22Alzheimer Disease (Alzheimer's Disease)
04/2024 - 01/2008
22Cardiovascular Diseases (Cardiovascular Disease)
03/2024 - 12/2010
22Lung Neoplasms (Lung Cancer)
03/2024 - 03/2005
22Colorectal Neoplasms (Colorectal Cancer)
12/2023 - 04/2002
21Immunoglobulin G4-Related Disease
01/2024 - 05/2014
20Arthritis (Polyarthritis)
04/2024 - 11/2008
20Type 2 Diabetes Mellitus (MODY)
04/2024 - 03/2012
20Hypertension (High Blood Pressure)
01/2024 - 05/2010
20Glioma (Gliomas)
03/2023 - 01/2011
19Colitis
04/2024 - 07/2012
19Non-alcoholic Fatty Liver Disease
12/2023 - 04/2013
19Autoimmune Diseases (Autoimmune Disease)
12/2023 - 09/2003
19Virus Diseases (Viral Diseases)
01/2023 - 06/2001
19Pancreatitis
02/2022 - 08/2007
18Liver Neoplasms (Liver Cancer)
01/2024 - 09/2004
18Thrombosis (Thrombus)
11/2023 - 04/2007
18Esophageal Neoplasms (Esophageal Cancer)
08/2023 - 06/2013
17Reperfusion Injury
12/2023 - 01/2003
17Allergic Rhinitis
09/2022 - 03/2006
16Heart Failure
10/2022 - 12/2004
16Hyperglycemia
09/2022 - 07/2008
15Dysbiosis
04/2024 - 05/2019
15Thrombocytopenia (Thrombopenia)
03/2024 - 01/2007

Drug/Important Bio-Agent (IBA)

187Proteins (Proteins, Gene)FDA Link
04/2024 - 06/2002
98Biomarkers (Surrogate Marker)IBA
12/2024 - 03/2010
87CytokinesIBA
04/2024 - 03/2009
67Messenger RNA (mRNA)IBA
12/2023 - 04/2003
63MicroRNAs (MicroRNA)IBA
01/2024 - 10/2012
60EnzymesIBA
05/2024 - 02/2003
47Glucose (Dextrose)FDA LinkGeneric
01/2024 - 03/2012
46RNA (Ribonucleic Acid)IBA
03/2024 - 06/2001
43Interleukin-6 (Interleukin 6)IBA
04/2024 - 02/2013
38LipidsIBA
04/2024 - 02/2010
38DNA (Deoxyribonucleic Acid)IBA
04/2024 - 02/2002
35Long Noncoding RNAIBA
03/2024 - 01/2014
34Therapeutic UsesIBA
01/2024 - 11/2004
32AntioxidantsIBA
01/2024 - 05/2008
31CarbonIBA
12/2024 - 09/2014
31VaccinesIBA
11/2023 - 09/2004
29Peptides (Polypeptides)IBA
01/2023 - 01/2008
28LipopolysaccharidesIBA
05/2024 - 01/2013
27GlucocorticoidsIBA
08/2023 - 02/2010
27CollagenIBA
06/2023 - 11/2006
26Immunoglobulin G (IgG)IBA
01/2024 - 04/2007
26AntibodiesIBA
01/2024 - 09/2004
25AntigensIBA
01/2023 - 02/2002
23Polysaccharides (Glycans)IBA
04/2024 - 11/2011
22InflammasomesIBA
05/2024 - 07/2015
22Reactive Oxygen Species (Oxygen Radicals)IBA
01/2024 - 01/2003
21Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2024 - 05/2004
19ChemokinesIBA
10/2023 - 10/2003
19Small Interfering RNA (siRNA)IBA
03/2023 - 05/2008
18TeaIBA
02/2024 - 11/2009
18Circular RNAIBA
01/2024 - 01/2018
18LigandsIBA
12/2023 - 05/2008
17Insulin (Novolin)FDA Link
10/2023 - 11/2009
17CholesterolIBA
01/2023 - 01/2008
16Immunosuppressive Agents (Immunosuppressants)IBA
01/2024 - 10/2010
16C-Reactive ProteinIBA
01/2024 - 08/2014
16Transcription Factors (Transcription Factor)IBA
02/2023 - 04/2004

Therapy/Procedure

205Therapeutics
04/2024 - 06/2002
56Drug Therapy (Chemotherapy)
03/2024 - 04/2002
35Immunotherapy
05/2024 - 03/2008
30Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2024 - 03/2010
22Radiotherapy
01/2023 - 12/2002
19Aftercare (After-Treatment)
12/2023 - 09/2011
16Lasers (Laser)
03/2024 - 02/2007
16Neoadjuvant Therapy
04/2022 - 09/2013
15Photochemotherapy (Photodynamic Therapy)
04/2024 - 01/2014